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pentobarbital will lessen the extent or outcome of isavuconazonium sulfate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.pentobarbital will reduce the extent or outcome of oliceridine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. If coadministration by using a CYP3A4 inducer is essential,